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Hubungan morfologi spermatozoa pada pria infertil dengan keberhasilan intrauterine insemination

Abstract

Background: Infertility is the inability of a married couple to achieve pregnancy within one year of unprotected sexual intercourse. Intrauterine Insemination (IUI) is one of the first-line treatments for couples experiencing infertility. One of the factors that can influence the success of IUI is spermatozoa morphology. This research aims to determine the relationship between spermatozoa morphology in infertile men and the success of IUI.

Methods: The research method employed in this study is an analytical cross-sectional research design. The research instruments include medical records and interview results from respondents using a Google form. Sampling is done through purposive sampling based on inclusion and exclusion criteria. The research was located in Kasih Ibu Denpasar Hospital from August until November 2023. 

Results: The study includes 35 samples, and upon examination, it was found that 10 respondents (28.6%) had normal sperm morphology ≥4%, while 25 respondents (71.4%) had normal sperm morphology <4%. In terms of IUI success, 6 individuals (17.1%) achieved pregnancy after undergoing IUI, while 29 individuals (82.9%) did not achieve pregnancy after the IUI procedure. Conclusion: The Fisher's Exact test results indicate no significant relationship between spermatozoa morphology and the success of IUI, with a p-value of 0.322.

Conclusion: The results of the Fisher's Exact test obtained were that there was no relationship between spermatozoa morphology and the success of IUI with a p value of 0.322.

 

Latar Belakang: Infertilitas adalah ketidakmampuan pasangan suami istri untuk mencapai kehamilan selama 1 tahun setelah melakukan hubungan seksual tanpa alat kontrasepsi. Intrauterine Insemination (IUI) merupakan salah satu penanganan lini pertama untuk pasangan suami istri yang mengalami gangguan infertilitas. Adapun salah satu faktor yang dapat memengaruhi keberhasilan IUI adalah morfologi spermatozoa. Penelitian ini dilakukan untuk mengetahui hubungan antara morfologi spermatozoa pada pria infertil dengan keberhasilan IUI. 

Metode: Metode penelitian ini adalah penelitian analitik cross-sectional. Instrumen penelitian ini adalah data rekam medis dan juga hasil wawancara responden dengan menggunakan google form. Pengambilan sampel menggunakan metode purposive sampling dan dipilih berdasarkan kriteria inklusi dan eksklusi. Penelitian ini bertempat di Rumah Sakit Kasih Ibu Denpasar dari bulan Agustus hingga November tahun 2023.

Hasil: Sampel pada penelitian ini didapatkan sebanyak 35 sampel dan setelah diteliti didapatkan responden yang memiliki morfologi sperma normal ≥4% adalah sebanyak 10 orang (28,6%) dan responden dengan morfologi sperma normal <4% adalah sebanyak 25 orang (71,4%). Sedangkan berdasarkan keberhasilan IUI, didapatkan sebanyak 6 orang (17,1%) berhasil mencapai kehamilan setelah menjalani prosedur IUI, sedangkan sebanyak 29 orang (82,9%) tidak berhasil mencapai kehamilan setelah menjalani prosedur IUI.

Kesimpulan: Adapun hasil uji Fisher’s Exact yang didapatkan adalah tidak terdapat hubungan antara morfologi spermatozoa dengan keberhasilan IUI dengan nilai p sebesar 0,322.

References

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How to Cite

Paramartha, N., I Gusti Ngurah Pramesemara, & I Made Oka Negara. (2024). Hubungan morfologi spermatozoa pada pria infertil dengan keberhasilan intrauterine insemination . Intisari Sains Medis, 15(1), 250–254. https://doi.org/10.15562/ism.v15i1.1916

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Nyoman Paramartha
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I Gusti Ngurah Pramesemara
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I Made Oka Negara
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ISM Journal